Advertisement

Impact of Restricting Early-term Deliveries on Adverse Neonatal Outcomes: A Statewide Analysis

Published:November 08, 2022DOI:https://doi.org/10.1016/j.ajogmf.2022.100797

      Abstract

      Background

      The “39-Week Rule” was adopted by the American College of Obstetricians and Gynecologists (ACOG) in 2009 to eliminate non-medically indicated (elective) deliveries prior to 39 weeks in an effort to improve neonatal outcomes.

      Objective

      Our primary objective was to quantify the effect of this policy change on adverse neonatal outcomes among a cohort of term births in South Carolina.

      Study Design

      De-identified data from all births in the state of South Carolina from 2000-2008 (prior to the 39-week rule) and 2013-2017 (after statewide implementation and enforcement of the rule) were obtained from the South Carolina Revenue and Fiscal Affairs Office. Demographic data and ICD9/10 codes were obtained for each birth. Our primary outcome was admission to a Neonatal Intensive Care Unit. Our secondary outcomes were respiratory morbidities (including respiratory distress syndrome and transient tachypnea of the newborn), hypoxic–ischemic encephalopathy, seizure, sepsis, birth injuries, hyperbilirubinemia, hypoglycemia, and feeding difficulties. Propensity score analysis was used to control for maternal age, Body Mass Index, race, gestational hypertension, infection, placental abruption, and gestational and pre-gestational diabetes. After stratification by propensity score, the Cochran-Mantel-Haenszel test was used to compare groups.

      Results

      620,121 infants were liveborn at term during the two study periods. After implementation of the 39-week rule, there was a significant reduction in early-term deliveries. In adjusted analyses, Neonatal Intensive Care Unit admission was significantly more common in the post-implementation period. Respiratory morbidities were also significantly more common post-implementation. In contrast, there were significant reductions in birth injuries and hyperbilirubinemia in the post-implementation period.

      Conclusions

      Implementation of the 39-week rule was associated temporally with an increase in adverse neonatal outcomes. The outcomes intended to be reduced by the 39-week rule, including Neonatal Intensive Care Unit admission and respiratory morbidity, appear to have increased in incidence despite adherence to the proposed guidelines.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Obstetrics & Gynecology MFM
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect