Vertical transmission of coronavirus disease 2019: severe acute respiratory syndrome coronavirus 2 RNA on the fetal side of the placenta in pregnancies with coronavirus disease 2019–positive mothers and neonates at birth

      Vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), is still a controversial issue and studies on transplacental transmission correlations are still limited. We report on our experience with placental SARS-CoV-2 markers of infection in a series of mothers who received a diagnosis of COVID-19 in their third trimester of pregnancy.
      To read this article in full you will need to make a payment


        • Wang F.
        • Flanagan J.
        • Su N.
        • et al.
        RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues.
        J Mol Diagn. 2012; 14: 22-29
        • Corman V.M.
        • Landt O.
        • Kaiser M.
        • et al.
        Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR.
        Euro Surveill. 2020; 25: 2000045
        • Lamouroux A.
        • Attie-Bitach T.
        • Martinovic J.
        • Leruez-Ville M.
        • Ville Y.
        Evidence for and against vertical transmission for SARS-CoV-2 (COVID-19).
        Am J Obstet Gynecol. 2020; ([Epub ahead of print])
        • Zeng H.
        • Xu C.
        • Fan J.
        • et al.
        Antibodies in infants born to mothers with COVID-19 pneumonia.
        JAMA. 2020; 323: 1848-1849
        • Wang S.
        • Guo L.
        • Chen L.
        • et al.
        A case report of neonatal COVID-19 infection in China.
        Clin Infect Dis. 2020; ([Epub ahead of print])
        • Penfield C.A.
        • Brubaker S.G.
        • Limaye M.A.
        • et al.
        Detection of SARS-COV-2 in placental and fetal membrane samples.
        Am J Obstet Gynecol MFM. 2020; ([Epub ahead of print])